Well it all kinda depends on what sort of stuff you want to make, and what skills you currently have. But let’s review a few general tips:
Start small. It’s fine to have great ambitions, but the fastest way to achieve those ambitions is to start with small projects and work up from there. Take us, for instance. The first things we made were shorts, not full episodes. They were only a couple minutes long and they only had a couple characters. Thus, we were able to finish them with only a small crew (which is all we had at the time), and in a relatively short amount of time.
Starting small allowed us to build up our skills and get feedback early on. If we’d started with something big, it would’ve taken forever and we would’ve had low morale and the whole thing might have collapsed.
Only do the basics. I’m in a separate project that tried to start with full animation, which took forever, until finally we abandoned the animation approach and went with animatics. If we’d started with animatics in the first place, we would’ve finished the first episode a lot sooner. (And in the case of PIAB, we decided to just do audio and skip animation entirely. Except now we have a bigger crew so that’s starting to change.)
Build a friendly team. If someone’s a jerk or a diva, don’t work with them. It’s just not worth it. Instead, work with people who are kind and reasonable. (The brony fandom has a lot of these, thankfully.)
Actually make a show. I once saw a group that had a youtube account, a deviantart account, a livestream account, a facebook account, and a bunch of other accounts…but they didn’t really have a show. You have to realize that all this other stuff is just fluff; it’s only useful if you actually have a show. So keep your focus on the show itself, and only add this other stuff when it makes sense.
Use gdrive (or something similar) to share files. It’s really annoying to email files back and forth all the time.
Learn what works for you. For us, we started on ponychan. Then later, when it made sense for us, we started talking on Skype instead. You have to be willing to adapt. Do whatever works for your particular group.
*hugs* I hope that helps.